Preview

The CIS Healthcare

Advanced search

The practice of self-medi­ cation and irrational use of antibacterial drugs in the Republic of Belarus

https://doi.org/10.21045/3033-6341-2025-1-1-32-41

Abstract

Introduction. One of the key drivers of antibiotic resistance is their irrational use and self-medication, which reaches up to 89% in some countries. To assess the current situation and develop targeted interventions aimed at curbing self-medication and inappropriate antibiotic use in the Republic of Belarus, a cross-sectional nationwide sociological study was conducted. The purpose of the study is to assess the level of irrational use and self-medication with antibacterial drugs among the population of the Republic of Belarus. Materials and methods. The study employed a questionnaire survey method using a specially designed and population-adapted questionnaire for the Republic of Belarus. Statistical analysis of results was performed using the Statistica software package and R-Studio. Results. The most commonly reported reasons for antibiotic use were predominantly irrational (53.2%), including acute respiratory viral infections, fever, cough, sore throat, headache. Key factors significantly associated with inappropriate antibiotic use: female gender, over-the-counter pharmacy purchases without prescription, initiation of therapy without laboratory confirmation, use of leftover antibiotics from previous treatments, lack of knowledge about proper antibiotic use, opposition to prescription-only regulations. Analysis revealed that 18.7% of respondents took antibiotics without a doctor’s prescription, of whom 69.5% initiated self-treatment independently. The study found that young age increased self-medication risk by 2.4 times, lack of higher education by 4.7 times, negative attitude toward prescription-only regulations by nearly threefold, and absence of pre-treatment test results by 2.9 times. Conclusion. The study findings demonstrate persistent challenges regarding irrational antibiotic use and self-medication practices among the Belarusian population, despite comparatively more favorable indicators relative to other countries.

About the Authors

N. E. Kolchanova
Gomel State Medical University
Russian Federation

Natalia E. Kolchanova – PhD in Medical sciences, Associate Professor of the Department of Otorhinolaryngology with courses in Ophthalmology and Dentistry 

Gomel 



V. P. Chigrina
Russian Research Institute of Health
Russian Federation

Valeriya P. Chigrina – leading specialist of Department for Strategic Development in Healthcare 

Moscow 



D. S. Tyufilin
Russian Research Institute of Health
Russian Federation

Denis S. Tyufilin – Head of the Department for Strategic Development in Healthcare

Moscow
 



A. Yu. Braga
Gomel State Medical University
Russian Federation

Anna Yu. Braga – Assistant of the Department of General and Clinical Pharmacology 

Gomel 



T. M. Sharshakova
Gomel State Medical University
Russian Federation

Tamara M. Sharshakova – Grand PhD in Medical sciences, Professor, Head of the Department of Public Health and Healthcare with course Faculty of Management Advanced Training and Retraining 

Gomel 



I. O. Stoma
Gomel State Medical University
Russian Federation

Igor O. Stoma – Grand PhD in Medical sciences, Professor, Rector 

Gomel 



O. S. Kobyakova
Russian Research Institute of Health
Russian Federation

Оlga S. Kobyakova – Corresponding Member of the RAS, Grand PhD in Medical sciences, Professor, Director 

Moscow 



References

1. Rossolini G.M., Arena F., Pecile P., Pollini S. Update on the antibiotic resistance crisis. Curr Opin Pharmacol. 2014;18:56–60. DOI: 10.1016/j.coph.2014.09.006

2. Muteeb G., Rehman M. T., Shahwan M., Aatif M. Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review. Pharmaceuticals (Basel). 2023;16(11):1615. DOI: 10.3390/ph16111615

3. Baran A., Kwiatkowska A., Potocki L. Antibiotics and Bacterial Resistance-A Short Story of an Endless Arms Race. Int J Mol Sci. 2023;24(6):5777. DOI: 10.3390/ijms24065777

4. Kumawat M., Nabi B., Daswani M. et al. Role of bacterial efflux pump proteins in antibiotic resistance across microbial species. Microb Pathog. 2023;181:106182. DOI: 10.1016/j.micpath.2023.106182

5. Ali S., Ryan L. WAAW – raising antimicrobial awareness in a tertiary University Hospital, Dublin. Ir J Med Sci. 2023;192(5):2283–2284. DOI: 10.1007/s11845‑022‑03263‑9

6. Marković-Peković V., Grubiša N. Self-medication with antibiotics in the Republic of Srpska community pharmacies: pharmacy staff behavior. Pharmacoepidemiol Drug Saf. 2012;21(10):1130–1133. DOI: 10.1002/pds.3218

7. Li B., Webster T. J. Bacteria antibiotic resistance: New challenges and opportunities for implant-associated orthopedic infections. J Orthop Res. 2018;36(1):22–32. DOI: 10.1002/jor.23656

8. Elden N.M.K., Nasser H. A., Alli A. et al. Risk Factors of Antibiotics Self-medication Practices among University Students in Cairo, Egypt. J. Med. Sci. 2020;8(E):7–12. DOI: 10.3889/oamjms.2020.3323

9. Mboya E.A., Sanga L. A., Ngocho J. S. Irrational use of antibiotics in the Moshi Municipality Northern Tanzania: a cross sectional study. Pan Afr Med J. 2018;31:165. DOI: 10.11604/pamj.2018.31.165.15991

10. Kolchanova N.E., Sharshakova T. M., Braga A.Yu. et al. Osobennosti priema antibakterial’nyh preparatov naseleniem v Respublike Belarus’ [Features of antibacterial drugs intake among the population of the Republic of Belarus]. Profilakticheskaya medicina [Russian Journal of Preventive Medicine]. 2024;27(10):15–22. DOI: 10.17116/profmed20242710115 (In Russ.).

11. Chigrina V.P., Tyufilin D. S., Kobyakova O. S. Priem antibakterial’nyh preparatov bez naznacheniya vracha v Rossijskoj Federacii [Taking antibacterial drugs without a doctor’s prescription in the Russian Federation]. Byulleten’ sibirskoj mediciny [Bulletin of Siberian Medicine]. 2023;22(4):147–153. DOI: 10.20538/1682‑0363‑2023‑4‑147‑155

12. Chigrina V.P., Tyufilin D. S., Kobyakova O. S. Racional’nost’ priema antibiotikov naseleniem Rossijskoj Federacii [Rationality of antibiotics administration by the population of the Russian Federation]. Profilakticheskaya medicina [Russian Journal of Preventive Medicine]. 2024;27(6);14. DOI: 10.17116/profmed20242706114 (In Russ.).

13. Al-Tarawneh A., Ali T., Al-Taani G. M. Public Patterns and Determinants of Antibiotic Self-Medication and Antibiotic Knowledge in Southern Jordan. Antibiotics. 2024;13(1):98. DOI: 10.3390/antibiotics13010098

14. Limwado G.D., Aron M. B., Mpinga K. et al. Prevalence of antibiotic self-medication and knowledge of antimicrobial resistance among community members in Neno District rural Malawi: A cross-sectional study. IJID Reg. 2024;13:100444. DOI: 10.1016/j.ijregi.2024.100444


Review

For citations:


Kolchanova N.E., Chigrina V.P., Tyufilin D.S., Braga A.Yu., Sharshakova T.M., Stoma I.O., Kobyakova O.S. The practice of self-medi­ cation and irrational use of antibacterial drugs in the Republic of Belarus. The CIS Healthcare. 2025;1(1):32-41. (In Russ.) https://doi.org/10.21045/3033-6341-2025-1-1-32-41

Views: 45


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 3033-6341 (Online)