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The impact of artificial intelligence technologies on active breast cancer detection: efficiency and scalability

https://doi.org/10.21045/3033-6341-2026-2-1-11-19

Abstract

Relevance. In the Russian Federation, breast cancer is the most common cancer among women, with the highest incidence and mortality rate (approximately 15.5%). Mammography is the standard method for mass screening aimed at early detection of malignant breast tumors and ensuring timely and optimal treatment outcome.

The purpose of the study: to evaluate the effectiveness of double reading of mammograms using artificial intelligence (AI) technologies.

Materials and methods. An epidemiological study was conducted from 2015 to 2024 using the URIS UMIAS, annual reference books, and federal statistical monitoring forms. In 2023, double reading for mammography using AI was developed and implemented based on data from the Moscow Experiment.

Results. Comparison of active breast cancer detection rates revealed distinct dynamics. In Moscow, detected cases increased from 40.9% (2015) to 52.3% (2023), with a pandemic-induced decline to 18.5% (2021) and post-COVID recovery at 9.6%/year. Nationwide, rates rose steadily from 37.2% to 44% (2.5%/year), without significant contrasts. The introduction of double reading of mammography AI decisively contributed to the significant, sustainable increase in active detection of breast cancer patients.

Conclusion. Artificial intelligence-enabled medical devices are recommended for transforming the double reading of mammography. Long-term implementation ensures a significant, sustainable increase in active detection of women with malignant breast tumors.

About the Authors

A. V. Vladzymyrskyy
Moscow Center for Diagnostics and Telemedicine; I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Anton V. Vladzymyrskyy, Doctor of sciences in medicine,

24/1 Petrovka street, Moscow, 119019;

8/2 Trubetskaya Street, Moscow, 119048



Yu. A. Vasilev
Moscow Center for Diagnostics and Telemedicine
Russian Federation

Yuri A. Vasilev, Doctor of sciences in medicine,

24/1, Petrovka street, Moscow, 119019.



A. V. Shakhov
Moscow Center for Diagnostics and Telemedicine
Russian Federation

Aleksandr V. Shakhov,

24/1, Petrovka street, Moscow, 119019.



R. I. Voloshin
Moscow Center for Diagnostics and Telemedicine
Russian Federation

Roman I. Voloshin,

24/1, Petrovka street, Moscow, 119019.



I. I. Vlazneva
Moscow Center for Diagnostics and Telemedicine
Russian Federation

Irina I. Vlazneva,

24/1, Petrovka street, Moscow, 119019.



V. P. Gamarina
Moscow Center for Diagnostics and Telemedicine
Russian Federation

Valentina P. Gamarina,

24/1, Petrovka street, Moscow, 119019.



E. A. Ryvkina
Moscow Center for Diagnostics and Telemedicine
Russian Federation

Elena A. Ryvkina,

24/1, Petrovka street, Moscow, 119019.



References

1. Polidanov M.A., Maslyakov V. V., Kuznetsova D. A., Kashikhin A. A., Volkov K. A., Tsukanova P. B. Dynamics of breast cancer incidence in the Russian Federation and European countries over the past 10 years. Psychosomatic and integrative studies. 2025; 11(3):1–6. (In Russ.).

2. El Masri J., Phadke S. Breast Cancer Epidemiology and Contemporary Breast Cancer Care: A Review of the Literature and Clinical Applications. Clin Obstet Gynecol. 2022 Sep 1; 65(3):461–481. DOI: 10.1097/GRF.0000000000000721.

3. Katsura C., Ogunmwonyi I., Kankam H. K., Saha S. Breast cancer: presentation, investigation and management. Br J Hosp Med (Lond). 2022 Feb 2; 83(2):1–7. DOI: 10.12968/hmed.2021.0459.

4. Malignant neoplasms in Russia in 2023 (incidence and mortality). Ed. by A. D. Kaprin [et al.]. – Moscow: P. A. Herzen Moscow Oncology Research Institute – branch of the National Medical Research Center of Radiology of the Ministry of Health of the Russian Federation; 2024. 276 p. (In Russ.).

5. Kontsevaya A.V., Balanova Yu.A., Myrzamatova A. O., Khudyakov M. B., Mukaneeva D. K., Drapkina O. M. Economic damage from oncological diseases associated with modifiable risk factors. Health Risk Analysis. 2020; 1:133–141. (In Russ.).

6. Zimatkina T.I., Aleksandrovich A. S. The analysis of the modern dynamics of incidence and mortality of the population of Republic of Belarus due to the breast cancer. Innovative scientific research. 2021;4–2(6):168–174.

7. Tupper H., Ghukasyan R., Bayburtyan A., Hovhannisyan M., Shekherdimian S. Breast Cancer Awareness and Screening Perceptions of Women in Yerevan, Armenia. Int J Public Health. 2024 May 16; 69:1607029. DOI: 10.3389/ijph.2024.1607029.

8. Aliyeva Sh.R.Z.G. Features of the epidemiology and surgical treatment of triple-negative breast cancer in Azerbaijan. Surgery. Eastern Europe. 2024; 13(3):409–417 (In Russ.).

9. Aldonina A. I. Breast cancer incidence and mortality among patients in the Republic of Belarus: formulation of the problem. Scientific review: current issues of theory and practice: collection of articles from the X International Scientific and Practical Conference. Penza; 2024. P. 178–182 (In Russ.).

10. Aitmagambetova M.A., Bekmukhambetov Ye. Zh., Smagulova G. A., Tulyayeva A. B., Koyshybaev A. K., Grjibovski A. M. Breast cancer in Western Kazakhstan: incidence, mortality and factors associated with survival. Human Ecology. 2021; 7:51–57.

11. Kasymova G.P., Utegenova A. B. Medical-demographic situation and the state of health of the adult population in connection with diseases of neoplasms in the Almaty Region of Kazakhstan. Oncology and Radiology of Kazakhstan. 2024; 3(73):11–18.

12. Rasulov S.R., Obidov D. S., Vasikhov Sh.A., Gayratova N. K. Epidemiological and clinical features of breast cancer in the Republic of Tajikistan: analysis for 2016–2023. Bulletin of postgraduate education in health care. 2025; 1:81–85 (In Russ.).

13. Normatova M.A., Juraeva N. S., Safarova G. R. Breast cancer incidence in females of reproductive age in khatlon region of the Republic of Tajikistan. Simurgh. 2021; 9:9–12.

14. Rim C.H., Lee W. J., Musaev B., Volichevich T. Y., Pazlitdinovich Z. Y., Lee H. Y., Nigmatovich T. M., Rim J. S. Consortium of Republican Specialized Scientific Practical-Medical Center of Oncology and Radiology and South Korean Oncology Advisory Group. Comparison of Breast Cancer and Cervical Cancer in Uzbekistan and Korea: The First Report of The Uzbekistan-Korea Oncology Consortium. Medicina (Kaunas). 2022 Oct 10; 58(10):1428. DOI: 10.3390/medicina58101428.

15. Chokoev A., Akhunbaev S., Kudaibergenova I., Soodonbekov E., Kulayev K., Ospanov K., Kuandykov Y., Telmanova Z., Makimbetov E., Igissinov N. Breast Cancer Incidence in Kyrgyzstan: Report of 15 Years of Cancer Registry. Asian Pac J Cancer Prev. 2022 May 1; 23(5):1603–1610. DOI: 10.31557/APJCP.2022.23.5.1603.

16. Duffy S.W., Tabár L., Yen A. M., Dean P. B., Smith R. A., Jonsson H. et al. Mammography screening reduces rates of advanced and fatal breast cancers: Results in 549,091 women. Cancer. 2020 Jul 1; 126(13):2971–2979. DOI: 10.1002/cncr.32859.

17. Newcomb P.A., Lantz P. M. Recent trends in breast cancer incidence, mortality, and mammography. Breast Cancer Res Treat. 1993 Nov; 28(2):97–106. DOI: 10.1007/BF00666422.

18. Chen Y., James J. J., Michalopoulou E., Darker I. T., Jenkins J. Performance of Radiologists and Radiographers in Double Reading Mammograms: The UK National Health Service Breast Screening Program. Radiology. 2022 Sep 13:212951. DOI: 10.1148/radiol.212951.

19. Euler-Chelpin M.V., Lillholm M., Napolitano G., Vejborg I., Nielsen M., Lynge E. Screening mammography: benefit of double reading by breast density. Breast Cancer Res Treat. 2018 Oct; 171(3):767–776. DOI: 10.1007/s10549-018-4864-1.

20. Kudryavtsev N.D., Kozhikhina D.D., Goncharova I.V., Shulkin I.M., Sharova D.E., Arzamasov K.M., Vladzymirskyy A.V. The impact of artificial intelligence on double reading of mammograms. Russian Journal of Preventive Medicine. 2024; 27(5):32–37. DOI: 10.17116/profmed20242705132. (In Russ.).

21. Artificial Intelligence in Radiation Diagnostics: Per Aspera Ad Astra. Ed. by Yu. A. Vasilev, A. V. Vladzimirskyy. Moscow: Publishing Solutions; 2025. 491 p. (In Russ.).

22. Vasilev Y.A., Kolsanov A. V., Arzamasov K. M., Vladzymyrskyy A. V., Omelyanskaya O. V., Semenov S. S., Axenova L. E. Evaluating the performance of artificial intelligence based software for digital mammography characterization. Digital Diagnostics. 2024; 5(4):695–711. DOI: 10.17816/DD625967 (In Russ.).

23. Arzamasov K.M., Vasilev Y. A., Vladzymyrskyy A. V., Omelyanskaya O. V., Shulkin I. M., Kozikhina D. D., Goncharova I. V., Gelezhe P. B., Kirpichev Y. S., Bobrovskaya T. M., Andreychenko A. E. An international non-inferiority study for the benchmarking of ai for routine radiology cases: chest x-ray, fluorography and mammography. Healthcare. 2023; 11(10).

24. Dembrower K., Crippa A., Colón E., Eklund M., Strand F. ScreenTrustCAD Trial Consortium. Artificial intelligence for breast cancer detection in screening mammography in Sweden: a prospective, population-based, paired-reader, non-inferiority study. Lancet Digit Health. 2023 Oct; 5(10): e703-e711. DOI: 10.1016/S2589–7500(23)00153-X.

25. Eisemann N., Bunk S., Mukama T., Baltus H., Elsner S. A., Gomille T., Hecht G., Heywang-Köbrunner S., Rathmann R., Siegmann-Luz K., Töllner T., Vomweg T. W., Leibig C., Katalinic A. Nationwide real-world implementation of AI for cancer detection in population-based mammography screening. Nat Med. 2025 Mar; 31(3):917–924. DOI: 10.1038/s41591-024-03408-6.

26. Branco P.E.S.C., Franco A. H.S., de Oliveira A. P., Carneiro I. M.C., de Carvalho L. M.C., de Souza J. I.N., Leandro D. R., Cândido E. B. Artificial intelligence in mammography: a systematic review of the external validation. Rev Bras Ginecol Obstet. 2024 Sep 4; 46: e-rbgo71. DOI: 10.61622/rbgo/2024rbgo71.

27. Larsen M., Aglen C. F., Lee C. I., Hoff S. R., Lund-Hanssen H., Lång K., Nygård J. F., Ursin G., Hofvind S. Artificial Intelligence Evaluation of 122 969 Mammography Examinations from a Population-based Screening Program. Radiology. 2022 Jun; 303(3):502–511. DOI: 10.1148/radiol.212381.

28. Marinovich M.L., Wylie E., Lotter W., Lund H., Waddell A., Madeley C., Pereira G., Houssami N. Artificial intelligence (AI) for breast cancer screening: BreastScreen population-based cohort study of cancer detection. EBioMedicine. 2023 Apr; 90:104498. DOI: 10.1016/j.ebiom.2023.104498.

29. Zukov R.A., Komissarova V. A., Safontsev I. P., Evminenko S. A. Artificial intelligence in breast cancer diagnosis: regional experience. Medical doctor and information technology. 2024; 4:72–84. DOI: 10.25881/18110193_2024_4_72.


Review

For citations:


Vladzymyrskyy A.V., Vasilev Yu.A., Shakhov A.V., Voloshin R.I., Vlazneva I.I., Gamarina V.P., Ryvkina E.A. The impact of artificial intelligence technologies on active breast cancer detection: efficiency and scalability. The CIS Healthcare. 2026;2(1):11-19. (In Russ.) https://doi.org/10.21045/3033-6341-2026-2-1-11-19

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