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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdravsng</journal-id><journal-title-group><journal-title xml:lang="ru">Здравоохранение стран СНГ</journal-title><trans-title-group xml:lang="en"><trans-title>The CIS Healthcare</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">3033-6341</issn><publisher><publisher-name>ФГБУ «ЦНИИОИЗ» Минздрава России</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21045/3033-6341-2026-2-2-12-18</article-id><article-id custom-type="elpub" pub-id-type="custom">zdravsng-34</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФАКТОРЫ РИСКА</subject></subj-group></article-categories><title-group><article-title>Эпидемиологические характеристики впервые выявленного сахарного диабета 2 типа в Республике Узбекистан</article-title><trans-title-group xml:lang="en"><trans-title>Epidemiological characteristics of type 2 diabetes mellitus first identified in the Republic of Uzbekistan</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2552-5028</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иброхимов</surname><given-names>Х. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Ibrokhimov</surname><given-names>Kh. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иброхимов Худойберди Хусанжон угли</p><p>проспект Мирзо‑Улугбека, д. 56, г. Ташкент, 100125</p></bio><bio xml:lang="en"><p>Ibrokhimov Khudoyberdi Kh.</p><p>56 Mirzo-Ulugbek Avenue, Tashkent, 100125</p></bio><email xlink:type="simple">khudoyberdi.ibrokhimov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8135-0824</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рахимова</surname><given-names>Г. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Rakhimova</surname><given-names>G. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рахимова Гульнара Нишановна, доктор медицинских наук, профессор</p><p>проспект Мирзо‑Улугбека, д. 56, г. Ташкент, 100125</p></bio><bio xml:lang="en"><p>Rakhimova Gulnara N., Doctor of Sciences in Medicine, Professor</p><p>56 Mirzo-Ulugbek Avenue, Tashkent, 100125</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-9979-7378</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алимов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Alimov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алимов Анвар Валиевич, доктор медицинских наук, профессор</p><p>проспект Мирзо‑Улугбека, д. 56, г. Ташкент, 100125</p></bio><bio xml:lang="en"><p>Alimov Anvar V., Doctor of Sciences in Medicine, Professor</p><p>56 Mirzo-Ulugbek Avenue, Tashkent, 100125</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бердыкулова</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Berdykulova</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бердыкулова Дилфуза Муратовна, кандидат медицинских наук</p><p>проспект Мирзо‑Улугбека, д. 56, г. Ташкент, 100125</p></bio><bio xml:lang="en"><p>Berdykulova Dilfuza M., Candidate of Sciences in Medicine</p><p>56 Mirzo-Ulugbek Avenue, Tashkent, 100125</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-0949-8279</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахроров</surname><given-names>К. У.</given-names></name><name name-style="western" xml:lang="en"><surname>Akhrorov</surname><given-names>K. U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ахроров Камиль Убайдуллаевич</p><p>ул. Паркентская, д. 51, г. Ташкент, 100007</p></bio><bio xml:lang="en"><p>Akhrorov Kamil U.</p><p>51 Parkentskaya street, Tashkent, 100007</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Асадова</surname><given-names>Н. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Asadova</surname><given-names>N. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Асадова Нозима Шерзодовна</p><p>проспект Мирзо‑Улугбека, д. 56, г. Ташкент, 100125</p></bio><bio xml:lang="en"><p>Asadova Nozima Sh.</p><p>56 Mirzo-Ulugbek Avenue, Tashkent, 100125</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Республиканский специализированный научно‑практический медицинский центр эндокринологии имени академика Ё. Х. Туракулова</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Republican Specialized Scientific and Practical Medical Center of Endocrinology named after Academician Y.Kh. Turakulov</institution><country>Uzbekistan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Центр развития профессиональной квалификации медицинских работников Министерства здравоохранения Республики Узбекистан</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Center for the Development of Professional Qualifications of Medical Workers</institution><country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>22</day><month>07</month><year>2026</year></pub-date><volume>2</volume><issue>2</issue><fpage>12</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иброхимов Х.Х., Рахимова Г.Н., Алимов А.В., Бердыкулова Д.М., Ахроров К.У., Асадова Н.Ш., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Иброхимов Х.Х., Рахимова Г.Н., Алимов А.В., Бердыкулова Д.М., Ахроров К.У., Асадова Н.Ш.</copyright-holder><copyright-holder xml:lang="en">Ibrokhimov K.K., Rakhimova G.N., Alimov A.V., Berdykulova D.M., Akhrorov K.U., Asadova N.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.health-cis.ru/jour/article/view/34">https://www.health-cis.ru/jour/article/view/34</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Сахарный диабет 2 типа остаётся одной из ведущих медико-социальных проблем современного здравоохранения и характеризуется неуклонным ростом распространённости, высокой частотой сердечно-сосудистых осложнений и значительным экономическим бременем. В последние годы всё больше данных свидетельствует о клинической и патогенетической гетерогенности сахарного диабета 2 типа, что обосновывает необходимость его более детального эпидемиологического и фенотипического анализа.</p></sec><sec><title>Цель исследования</title><p>Цель исследования: оценить динамику выявляемости и первичной заболеваемости сахарным диабетом 2 типа в Республике Узбекистан в 2022–2024 гг., а также определить эпидемиологический контекст возможного наличия его различных фенотипов.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведено ретроспективное описательное эпидемиологическое исследование на основе агрегированных данных официальной статистики по впервые выявленным случаям сахарного диабета 2 типа в 2022–2024 гг. Анализ выполнен с учётом возраста (18–29, 30–59, ≥60 лет) и региона проживания. Рассчитывались показатели заболеваемости на 100 тыс. населения.</p></sec><sec><title>Результаты</title><p>Результаты. В Республике Узбекистан отмечен устойчивый рост распространённости и заболеваемости сахарным диабетом, особенно выраженный после внедрения скрининга (2022 г.). Более 60% всех новых случаев сахарного диабета 2 типа приходятся на лиц трудоспособного возраста 30–59 лет, что указывает на значительную социально-экономическую нагрузку. Доля пациентов ≥60 лет за 2022–2024 гг. увеличилась с 37,5 до 39,4%. Заболеваемость в группе ≥60 лет превышала показатели в группе 30–59 лет более чем в 2,5 раза и характеризовалась выраженной региональной вариабельностью. Доля молодых пациентов 18–29 лет оставалась низкой, однако за период наблюдения отмечена тенденция к росту.</p></sec><sec><title>Заключение</title><p>Заключение. Возрастные и региональные особенности выявляемости и первичной заболеваемости сахарным диабетом 2 типа формируют предпосылки для наличия различных популяционных фенотипов заболевания в Республике Узбекистан и обосновывают необходимость дальнейших клинико-функциональных исследований с учётом современных фенотипических классификаций.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. Type 2 diabetes mellitus (T2DM) remains one of the leading medical and social problems in modern healthcare, characterized by a steady increase in prevalence, a high frequency of cardiovascular complications, and a significant economic burden. In recent years, more and more data indicate the clinical and pathogenetic heterogeneity of DM2, which casts doubt on its consideration as a homogeneous disease and justifies the need for more detailed epidemiological and phenotypic analysis.</p></sec><sec><title>The purpose of the study</title><p>The purpose of the study: assessment of the dynamics and age-related characteristics of type 2 diabetes mellitus first identified in the Republic of Uzbekistan in the period 2022–2024 against the background of the implementation of population screening, as well as determining the epidemiological context for the possible existence of various phenotypes of DM2.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. A retrospective descriptive epidemiological study was conducted based on aggregated data from official statistics on newly identified cases of type 2 diabetes mellitus in 2022–2024. The analysis was performed taking into account age (18–29, 30–59, ≥60 years), gender, and the region of residence. The proportion of age groups and morbidity rates per 100,000 population were calculated.</p></sec><sec><title>Results</title><p>Results. In Uzbekistan, a steady increase in the prevalence and incidence of diabetes mellitus has been observed, especially pronounced after the introduction of screening since 2022. More than 60% of all new cases of AD2 annually occur in working-age individuals aged 30–59, indicaing a significant socio-economic burden. The proportion of patients ≥60 years old consistently increased (37.5% to 39.4%), reflecting the “aging” of the identified structure. Morbidity in the ≥60 age group exceeded the indicators of the 30–59 age group by more than 2.5 times and was characterized by pronounced regional variability. The proportion of young patients aged 18–29 remained low, however, during the observation period, a trend towards growth was noted, which indicates the «youthing» of DM2.</p></sec><sec><title>Conclusion</title><p>Conclusion. The identified age and regional characteristics of newly diagnosed type 2 diabetes form the prerequisites for the existence of various population phenotypes of the disease in Uzbekistan and justify the need for further clinical and functional studies, taking into account modern phenotypic classifications.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>эпидемиология</kwd><kwd>фенотипы</kwd><kwd>возрастная структура</kwd><kwd>заболеваемость</kwd><kwd>Республика Узбекистан</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes mellitus</kwd><kwd>epidemiology</kwd><kwd>phenotypes</kwd><kwd>age structure</kwd><kwd>morbidity</kwd><kwd>Republic of Uzbekistan</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">IDF Diabetes Atlas 11th Edition – 2025. 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